Sunday, November 1, 2009

Kidney transplants are generally safe for patients with lupus

Persons with a history of lupus, a serious inflammation of the kidney transplant often develop lupus nephritis in their new body will, according to a statement from the American Society of Nephrology 42nd Annual Meeting and Scientific Exhibition presented at San Diego, CA. The results show that no one should take in lupus research by a kidney transplant if they have a need. Individuals with the autoimmune disease systemic erythematosus (lupus) is a series of medical complications, experiences such as lupus nephritis, an inflammatory renal disease. Previous studies give conflicting results regarding the frequency and severity of lupus nephritis in patients with a history of lupus who underwent a kidney transplant. Some studies conclude that lupus nephritis is of little importance, while others indicate that this condition, the risk of renal failure and increase the risk of death in recipients of kidney transplants.

Gabriel Contreras, MD, MPH (University of Miami), and colleagues conducted a comprehensive evaluation of the frequency of lupus nephritis in recipients of kidney transplants and to determine the risk for this condition, the patient did. They obtained data from the United Network for Organ Sharing, and studied 6850 patients with a history of renal transplantation, lupus received between 1987 and 2006.

Researchers have found that lupus nephritis rarely developed in kidney transplanted patients with lupus, it occurred in 2.44% of individuals in the study. If this does not work, lupus nephritis with LED 4 times more relative risk for failure of kidney transplantation, however, given the overall risk for loss of the new organ in the development of lupus in the kidney transplant was only 7 %. During the study period of 19 years, 12.7% of patients died, with only 0.4% of patients die in the group with the development of lupus in the kidney transplant. The researchers also found that African-Americans and young women were more likely to develop lupus nephritis in the transplanted kidney. Receiving a kidney transplant before or after the start of dialysis had no effect on risk. The nature of the renal transplant (deceased VS) from a living donor did not influence the risk for recipients of lupus nephritis.

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