Paracetamol may be linked to asthma in children and adults

Recent studies show that the widely used pain reliever paracetamol with increased risk of asthma may be linked, suspended wheezing in children and adults using drugs. Researchers at the University of British Columbia, Vancouver, BC, Canada, conducted a systematic review and meta-analysis of 19 clinical studies (total subjects = 425140) which compared the risk of asthma or wheezing in acetaminophen exposure. The analysis showed that the pooled odds ratio (odds ratio for the combination of all studies) for the treatment of asthma among users of paracetamol was 1.63. The risk of asthma used in children increased diagnosis of asthma or paracetamol in the first year of life was 1.60 and 1.47, respectively.

In addition, the results show a slight increased risk of asthma and respiratory problems in the prenatal use of paracetamol by mothers. Researchers suspect that the lack of inhibition of cyclooxygenase acetaminophen, the key enzyme in the inflammatory response of asthma to be involved, explain the possible link between paracetamol use and asthma .